Tripling the detection view of high-frequency linear-array-based photoacoustic computed tomography by using two planar acoustic reflectors
Abstract
Background: Linear-array-based photoacoustic computed tomography (PACT) suffers from a limited view. Circular scanning does increase the detection view angle but is time-consuming. Therefore, it is desirable to increase the detection view angle of linear-array-based PACT without sacrificing imaging speed. Methods: Two planar acoustic reflectors placed at 120 degrees to each other were added to a linear-array-based PACT system. Each reflector redirects originally undetectable photoacoustic waves back to the transducer array elements, and together they triple the original detection view angle of the PACT system. Results: Adding two reflectors increased the detection view angle from 80 to 240 degrees. As a comparison, a single-reflector PACT has a detection view angle of only 160 degrees. A leaf skeleton phantom with a rich vascular network was imaged with the double-reflector PACT, and most of its features were recovered. Conclusions: The two acoustic reflectors triple the detection view angle of a linear-array-based PACT without compromising the original imaging speed. This nearly full-view detection capability produces higher-quality images than single-reflector PACT or conventional PACT without reflectors.
Additional Information
© 2015 AME Publishing Company. Submitted Sep 02, 2014. Accepted for publication Oct 19, 2014. The authors appreciate Prof. James Ballard's close reading of the manuscript. This work was sponsored by National Institute of Health (NIH) grants DP1 EB016986 (NIH Director's Pioneer Award), R01 CA186567 (NIH Director's Transformative Research Award), R01 EB016963, R01 CA159959 and S10 RR026922. Disclosure: L.W. has a financial interest in Microphotoacoustics, Inc. and Endra, Inc., which, however, did not support this work. K.M. has a financial interest in Microphotoacoustics, Inc.Attached Files
Published - qims-05-01-057.pdf
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Additional details
- PMCID
- PMC4312304
- Eprint ID
- 68498
- Resolver ID
- CaltechAUTHORS:20160617-154410593
- NIH
- DP1 EB016986
- NIH
- R01 CA186567
- NIH
- R01 EB016963
- NIH
- R01 CA159959
- NIH
- S10 RR026922
- Created
-
2016-06-18Created from EPrint's datestamp field
- Updated
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2021-11-11Created from EPrint's last_modified field