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Published 1979 | public
Journal Article

Specific protection from phenocopy induction by heat shock


Mild heat treatments applied to whole animals or cell cultures of Drosophila prior to lethal heat shocks result in increased survival and protection against phenocopy induction. The optimal condition for the preliminary mild heat treatment is that which induces the synthesis of heat‐shock proteins but does not turn off the protein synthesis that is in progress. Recovery of protein synthesis but not RNA synthesis following a drastic heat shock is much enhanced by the pretreatments. The results suggest that the protection for survival and against phenocopy induction is due to storage of messenger RNA.

Additional Information

© 1979 Wiley‐Liss, Inc. Manuscript accepted: 14 September 1979; Manuscript received: 16 July 1979.

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August 22, 2023
October 18, 2023