Welcome to the new version of CaltechAUTHORS. Login is currently restricted to library staff. If you notice any issues, please email coda@library.caltech.edu
Published January 2012 | public
Book Section - Chapter

A 3D parylene scaffold cage for culturing retinal pigment epithelial cells


This work reports a 3D parylene scaffold cage for culturing stem-cell-differentiated retinal pigment epithelial (RPE) cells for the therapy of age-related macular degeneration, which is caused by degenerated permeability of the Bruch's membrane first and then the loss of RPE cells. This reported cage can support sufficient nutrient permeation to nourish the RPE cells inside with in vivo like morphology. Compared to previous single layer scaffold substrates, this cage can effectively prevent the undesirable cell migration away from the scaffold.

Additional Information

© 2012 IEEE. Date of Current Version: 15 March 2012. This work is supported by the California Institute of Regenerative Medicine (CIRM); Disease Team Award; Grant DR1-01444.

Additional details

August 19, 2023
October 23, 2023