Published April 2001 | Version public
Journal Article

Can stem cells cross lineage boundaries?

  • 1. ROR icon California Institute of Technology
  • 2. ROR icon Salk Institute for Biological Studies
  • 3. ROR icon Stanford University

Abstract

Stem cells have traditionally been characterized as either embryonic (pluripotent) or organ-specific. Recent work suggests that the latter can "transdifferentiate" into other cell types, carrying significant implications for possible clinical use of these cells. Here the authors critically examine the existing data, and suggest standards for the evaluation of these and future studies.

Additional Information

© 2001 Nature Publishing Group. D.J.A. is an Investigator of the Howard Hughes Medical Institute; F.H.G. is supported by the National Institutes of Health and I.J.W. is supported by the National Institutes of Health.

Additional details

Identifiers

Eprint ID
55714
Resolver ID
CaltechAUTHORS:20150311-150256418

Funding

Howard Hughes Medical Institute (HHMI)
NIH

Dates

Created
2015-03-26
Created from EPrint's datestamp field
Updated
2021-11-10
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