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Published May 21, 2014 | public
Journal Article

Discovery of the Biology of the Ubiquitin System


This article, about the discovery of the biology of the ubiquitin system, describes my laboratory's main contribution to date, and stems, in part, from previous historical summaries. Another antecedent is the interview given in 2006 to Dr Istvan Hargittai, a distinguished Hungarian chemist. It described my life and science, including the early years in Moscow (Russia), the 1977 emigration from the former Soviet Union to the United States, and scientific work that ensued.

Additional Information

© 2014 American Medical Association. Conflict of Interest Disclosures: The author has completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest and none were reported. Funding/Support: The studies are supported by grants from the National Institutes of Health. Role of the Sponsor: The National Institutes of Health had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication. Additional Contributions: I thank former and present colleagues in the laboratory whom I have had the privilege to collaborate with over the last 3 decades.

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October 26, 2023