Published June 1, 2013
| Published
Journal Article
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Chip-scale fluorescence microscope based on a silo-filter complementary metal-oxide semiconductor image sensor
Abstract
We demonstrate a silo-filter (SF) complementary metal-oxide semiconductor (CMOS) image sensor for a chip-scale fluorescence microscope. The extruded pixel design with metal walls between neighboring pixels guides fluorescence emission through the thick absorptive filter to the photodiode of a pixel. Our prototype device achieves 13 μm resolution over a wide field of view (4.8 mm × 4.4 mm). We demonstrate bright-field and fluorescence longitudinal imaging of living cells in a compact, low-cost configuration.
Additional Information
© 2013 Optical Society of America. Received March 13, 2013; accepted April 8, 2013; posted April 16, 2013 (Doc. ID 186601); published May 21, 2013. This project is funded by the NIH under grant 1R01AI096226-01.Attached Files
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Additional details
- PMCID
- PMC3740726
- Eprint ID
- 39358
- Resolver ID
- CaltechAUTHORS:20130715-100248148
- NIH
- 1R01AI096226-01
- Created
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2013-07-15Created from EPrint's datestamp field
- Updated
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2021-11-09Created from EPrint's last_modified field