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Published January 28, 2010 | public
Journal Article

Controlling biological networks by time-delayed signals


This paper describes the use of time-delayed feedback to regulate the behaviour of biological networks. The general ideas on specific transcriptional regulatory and neural networks are demonstrated. It is shown that robust yet tunable controllers can be constructed that provide the biological systems with model-engineered inputs. The results indicate that time delay modulation may serve as an efficient biocompatible control tool.

Additional Information

© 2010 The Royal Society. One contribution of 13 to a Theme Issue 'Delayed complex systems'. This research was sponsored by the National Science Foundation under grant NSF-0547606 and by the Institute for Collaborative Biotechnologies under grant DAAD19-03-D004 from the US Army Research Office.

Additional details

August 21, 2023
October 19, 2023