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Published February 24, 2009 | Published
Book Section - Chapter Open

A fast 512-element ring array photoacoustic imaging system for small animals


A 512-element photoacoustic tomography system for small animal imaging using a ring ultrasound array has been developed. The system features a 5 MHz piezocomposite transducer array formed into a complete circular aperture. Custom receiver electronics consisting of dedicated preamplifiers, 8:1 multiplexed post-amplifiers, and a 64-channel data acquisition module provide full tomographic imaging at up to 8 frames/second. We present details of the system design along with characterization results of the resolution, imaging volume, and sensitivity. Small animal imaging performance is demonstrated through images of mice brain vasculature at different depths and real-time spectroscopic scans. This system enables real-time tomographic imaging for functional photoacoustic studies for the first time.

Additional Information

© 2009 Society of Photo-Optical Instrumentation Engineers (SPIE). We acknowledge partial support from NIH grants NIH R01EB002136 and the Patrick and Catherine Weldon Donaghue Research Foundation.

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