Published May 15, 2001 | Version Published
Journal Article Open

Phase-dispersion optical tomography

Abstract

We report on phase-dispersion optical tomography, a new imaging technique based on phase measurements using low-coherence interferometry. The technique simultaneously probes the target with fundamental and second-harmonic light and interferometrically measures the relative phase shift of the backscattered light fields. This phase change can arise either from reflection at an interface within a sample or from bulk refraction. We show that this highly sensitive 5 phase technique can complement optical coherence tomography, which measures electric field amplitude, by revealing otherwise undetectable dispersive variations in the sample.

Additional Information

© 2001 Optical Society of America Received October 25, 2000 This work was carried out at the Laser Biomedical Research Center of the Massachusetts Institute of Technology and was supported by National Institutes of Health (NIH) grant P41-RR02594, National Science Foundation grant 9708265-CHE, and a grant from Hamamatsu Corporation. A. Wax was supported by NIH National Research Service Award 1 F32 RR05075-01. We acknowledge helpful comments about the mirrors from Anna Wang and Earl Rudisill of Newport Corporation.

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Identifiers

Eprint ID
3324
Resolver ID
CaltechAUTHORS:YANol01b

Funding

NIH
P41-RR02594-18
NSF
CHE-9708265
Hamamatsu Corporation
NIH Postdoctoral Fellowship
1 F32 RR05075-01

Dates

Created
2006-05-30
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Updated
2020-03-09
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