Ultrafast Dynamics in DNA-Mediated Electron Transfer: Base Gating and the Role of Temperature
The ultrafast dynamics of electron transfer (ET) between bases in DNA have been determined to elucidate the critical role of base-pair gating on the timescale of the electron transport and the temperature dependence of the rates. ET occurs only through DNA duplexes that adopt a specific, well-coupled alignment of bases (ET-active; see picture). Descriptions of ET dynamics must include fluctuations of DNA bases.
© 2003 Wiley-VCH Verlag GmbH & Co. Received: September 9, 2003. Article first published online: 8 Dec 2003. This work was made possible through the support of the Laboratory for Molecular Sciences and the NSF. M.A.O. and H.-C.B. are grateful to NSERC and the Wenner-Gren Foundation, respectively, for postdoctoral fellowships.