Published August 1999 | Version public
Journal Article

Energy functions for protein design

Abstract

Recent successes in protein design have illustrated the promise of computational approaches. These methods rely on energy expressions to evaluate the quality of different amino acid sequences for target protein structures. The force fields optimized for design differ from those typically used in molecular mechanics and molecular dynamics calculations.

Additional Information

© 1999 Elsevier Science Ltd. Available online 22 September 1999. We wish to thank AG Street for helpful comments on the manuscript. This work was supported by the Howard Hughes Medical Institute (SLM), the Helen G and Arthur McCallum Foundation (DBG), a National Institutes of Health NRSA training grant and the Caltech Initiative in Computational Molecular Biology program, awarded by the Burroughs Wellcome Fund (SAM).

Additional details

Identifiers

Eprint ID
24160
Resolver ID
CaltechAUTHORS:20110621-154505395

Funding

Howard Hughes Medical Institute (HHMI)
Helen G and Arthur McCallum Foundation
NIH NRSA Training Grant
Burroughs Wellcome Fund

Dates

Created
2011-06-21
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Updated
2021-11-09
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