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Published May 2, 2024 | Submitted
Discussion Paper Open

Exploiting ChatGPT for Diagnosing Autism-Associated Language Disorders and Identifying Distinct Features

Abstract

Diagnosing language disorders associated with autism is a complex and nuanced challenge, often hindered by the subjective nature and variability of traditional assessment methods. Traditional diagnostic methods not only require intensive human effort but also often result in delayed interventions due to their lack of speed and specificity. In this study, we explored the application of ChatGPT, a state-of-the-art large language model, to overcome these obstacles by enhancing diagnostic accuracy and profiling specific linguistic features indicative of autism. Leveraging ChatGPT's advanced natural language processing capabilities, this research aims to streamline and refine the diagnostic process. Specifically, we compared ChatGPT's performance with that of conventional supervised learning models, including BERT, a model acclaimed for its effectiveness in various natural language processing tasks. We showed that ChatGPT substantially outperformed these models, achieving over 13% improvement in both accuracy and F1-score in a zero-shot learning configuration. This marked enhancement highlights the model’s potential as a superior tool for neurological diagnostics. Additionally, we identified ten distinct features of autism-associated language disorders that vary significantly across different experimental scenarios. These features, which included echolalia, pronoun reversal, and atypical language usage, were crucial for accurately diagnosing ASD and customizing treatment plans. Together, our findings advocate for adopting sophisticated AI tools like ChatGPT in clinical settings to assess and diagnose developmental disorders. Our approach not only promises greater diagnostic precision but also aligns with the goals of personalized medicine, potentially transforming the evaluation landscape for autism and similar neurological conditions.

Copyright and License

This work is licensed under a CC BY 4.0 License.

Funding

This research was supported by the NSF (IIS-2114644) and NIH (R01MH129426). The funders had no rolein study design, data collection and analysis, decision to publish, orpreparation of the manuscript.

Contributions

C.H., L.K.P., S.W., X.L. designed research. L.K.P. performed experiments. C.H., W.L., M.R., and X.Y.analyzed data. C.H., S.W., and X.L. wrote the paper. All authors discussed the results and contributedtoward the manuscript.

Conflict of Interest

The authors declare no conflict of interest.

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Additional details

Created:
June 11, 2024
Modified:
June 11, 2024