Published June 2002
| public
Journal Article
Induction of the neural crest: a multigene process
- Creators
- Knecht, Anne K.
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Bronner-Fraser, Marianne
Abstract
In the embryo, the neural crest is an important population of cells that gives rise to diverse derivatives, including the peripheral nervous system and the craniofacial skeleton. Evolutionarily, the neural crest is of interest as an important innovation in vertebrates. Experimentally, it represents an excellent system for studying fundamental developmental processes, such as tissue induction. Classical embryologists have identified interactions between tissues that lead to neural crest formation. More recently, geneticists and molecular biologists have identified the genes that are involved in these interactions; this recent work has revealed that induction of the neural crest is a complex multistep process that involves many genes.
Additional Information
© 2002 Nature Publishing Group. The authors thank T. Moreno for help with the figures, and M. García-Castro and M. Albrecht for critical reading of the manuscript.Additional details
- Eprint ID
- 56496
- DOI
- 10.1038/nrg819
- Resolver ID
- CaltechAUTHORS:20150408-145638064
- Created
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2015-04-08Created from EPrint's datestamp field
- Updated
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2021-11-10Created from EPrint's last_modified field