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Published September 1, 1933 | public
Journal Article Open

Oxidation reduction potential of ascorbic acid (Vitamin C)


The measurement of the oxidation-reduction potential of ascorbic acid (Vitamin C) is desirable in the elucidation of its physiological action. Two attempts have been made to measure this potential. Georgescu(1) concluded that he had obtained a thermodynamically reversible potential at pH 6.9, and 7.0 at 20°C. From the data presented, however, it is not possible to accept this interpretation without reservation.

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Copyright © 1933 by the National Academy of Sciences. Communicated August 4, 1933. We wish to acknowledge our indebtedness to Professor A. von Szent-Gyorgyi for his gift of the specimen of pure ascorbic acid used in this investigation, and to thank him heartily for his generosity.


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