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Published June 15, 1998 | Published
Journal Article Open

Frequency-swept ultrasound-modulated optical tomography of scattering media


A novel frequency-swept ultrasound-modulated optical tomography technique was developed to image scattering media. A frequency-swept ultrasonic wave was used to modulate the laser light passing through a scattering medium. The modulated light was received by an optical detector and was heterodyned with a reference frequency sweep. The heterodyned signal was recorded in the time domain and was then analyzed in the frequency domain to yield a one-dimensional image along the ultrasonic axis. Multiple one-dimensional images obtained at various positions perpendicular to the ultrasonic axis were combined to yield a two-dimensional tomographic image of the medium.

Additional Information

© 1998 Optical Society of America. Received January 26, 1998. We thank X. Zhao for experimental assistance with the electronics. This project was sponsored by National Institutes of Health grants R29 CA68562 and R01 CA71980.

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