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Published November 2006 | Published
Journal Article Open

Methods and application areas of endoscopic optical coherence tomography


We review the current state of research in endoscopic optical coherence tomography (OCT). We first survey the range of available endoscopic optical imaging techniques. We then discuss the various OCT-based endoscopic methods that have thus far been developed. We compare the different endoscopic OCT methods in terms of their scan performance. Next, we examine the application range of endoscopic OCT methods. In particular, we look at the reported utility of the methods in digestive, intravascular, respiratory, urinary and reproductive systems. We highlight two additional applications—biopsy procedures and neurosurgery—where sufficiently compact OCT-based endoscopes can have significant clinical impacts.

Additional Information

© 2006 Society of Photo-Optical Instrumentation Engineers. Paper 06069RR received Mar. 27, 2006; revised manuscript received Aug. 10, 2006; accepted for publication Aug. 12, 2006; published online Dec. 18, 2006. The authors would like to thank Benjamin Paz (MD), Michael A. Choma (MD, PhD), David Raphael (MD, PhD), Alice Yung (MD), and Marinko Sarunic (PhD) for useful suggestions and comments. This work is supported by funding from National Institutes of Health Grant No. 5R21EB004602-02.

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