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Published May 2004 | Supplemental Material
Journal Article Open

Rewritable Memory by Controllable Nanopatterning of DNA


Fabricating a nanostructure capable of reversibly patterning molecules is a fundamental goal within nanotechnology, underlying diverse processes such as information storage, scaffold-assisted assembly, and molecular transport. Here, we describe a DNA scaffold supporting a one-dimensional array of independently and reversibly addressable sites at 7 nm spacing. As a proof-of-concept, we demonstrate robust functioning of the device as rewritable memory. The bit state of each address is controlled by specific DNA strands with external readout provided by fluorescence measurements.

Additional Information

© 2004 American Chemical Society. Received 3 March 2004. Published online 13 April 2004. Published in print 1 May 2004. We wish to thank S. L. Mayo for comments on the manuscript. The following research support is gratefully acknowledged:  DARPA and the Air Force Research Laboratory under agreement F30602-01-2-0561, the Ralph M. Parsons Foundation, and the Charles Lee Powell Foundation.

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