Published January 5, 2023 | Version public
Journal Article

Gifts hidden in shadowy genome islands

  • 1. ROR icon California Institute of Technology

Abstract

Despite being typically perceived as "clonal" organisms, bacteria and archaea possess numerous mechanisms to share and co-opt genetic material from other lineages. Several mechanisms for horizontal gene transfer have been discovered, but the high mosaicity observed in many bacterial genomes outscales that explained by known mechanisms, hinting at yet undiscovered processes. In this issue of Cell, Hackl et al. introduce a new category of mobile genetic elements called tycheposons, providing a novel mechanism that contributes to the prodigious genomic diversity within microbial populations. The discovery and characterization of tycheposons prompts a reevaluation of microbial diversification in complex environments.

Additional Information

© 2022 Elsevier. V.J.O. and D.R.U. are supported in part by the U.S. Department of Energy, Office of Science, Office of Biological and Environmental Research under Award Number (DE-SC0022991). D.R.U. is a National Science Foundation - Ocean Sciences Postdoctoral Research Fellow (2126631) and V.J.O. is a science fellow in the Canadian Institute for Advanced Science in the Earth 4D program. The authors declare no competing interests.

Additional details

Identifiers

Eprint ID
121079
Resolver ID
CaltechAUTHORS:20230420-614686900.8

Funding

Department of Energy (DOE)
DE-SC0022991
NSF Postdoctoral Fellowship
OCE-2126631
Canadian Institute for Advanced Research (CIFAR)

Dates

Created
2023-05-22
Created from EPrint's datestamp field
Updated
2023-05-22
Created from EPrint's last_modified field

Caltech Custom Metadata

Caltech groups
Division of Biology and Biological Engineering (BBE)