Published March 2002 | Version public
Journal Article

Evaluation of the energetic contribution of an ionic network to beta-sheet stability

Abstract

We have evaluated the interaction energy of a three-residue ionic network constructed on the β-sheet surface of protein G using double mutant cycles. Although the two individual ion pairs were each stabilizing by ~0.6 kcal/mol, the excess gain in stability for the triad was small (0.06 kcal/mol).

Additional Information

© 2002 The Protein Society. Received June 19, 2001; Accepted November 30, 2001. Article first published online: 13 Apr. 2009.

Additional details

Identifiers

PMCID
PMC2373463
Eprint ID
25478
DOI
10.1110/ps.23502
Resolver ID
CaltechAUTHORS:20110928-153816383

Dates

Created
2011-09-29
Created from EPrint's datestamp field
Updated
2021-11-09
Created from EPrint's last_modified field