Welcome to the new version of CaltechAUTHORS. Login is currently restricted to library staff. If you notice any issues, please email coda@library.caltech.edu
Published July 5, 2005 | public
Book Section - Chapter Open

Microfluidic detection and analysis by integration of evanescent wave sensing with thermocapillary actuation


An integrated system capable of microfluidic actuation, detection and sensing is described which combines evanescent wave sensing with thermocapillary manipulation. Liquid droplets or streams transported across the beam path of a planar thin film waveguide, which encapsulates the microheater array, induce attenuation of the propagating waveguide modes. The attenuated signal is used to monitor droplet location, dye concentration in aqueous solutions and reaction kinetics for enzymatic hydrolysis of the sugar X-galactose by beta-galactosidase.

Additional Information

This work was funded by the NASA Microgravity Fluid Physics Program and the US Army TACOM-ARDEC. JPV wishes to thank Dr. P. K. Tien of Bell Labs for helpful discussions. SMT gratefully acknowledges the Moore Distinguished Scholar Program at Caltech, where she is currently on leave, for the generous hospitality and financial support extended during her stay.


Files (806.0 kB)
Name Size Download all
806.0 kB Preview Download

Additional details

August 22, 2023
October 16, 2023