Control of mitochondrial dynamics by a fusogenic lipid

Creators: Yang, Zheng; Chan, David C.¹

1. California Institute of Technology

Abstract

Mitochondrial fusion enables cooperation between the mitochondrial population and is critical for mitochondrial function. Phosphatidic acid (PA) on the mitochondrial surface has a key role in mitochondrial fusion. A recent study by Su et al. shows that the nucleoside diphosphate (NDP) kinase NME3 recognizes PA and mediates its effects on mitochondrial dynamics.

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Acknowledgement

This work was supported by the NIH grant R35GM127147.

Conflict of Interest

The authors have no conflicts of interest to declare.

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Resource type: Journal Article
Publisher: Cell Press
Published in: Trends in Cell Biology, 33(12), 1005-1006, ISSN: 0962-8924.
Languages: English

Created:: October 30, 2023
Modified:: June 17, 2024