Published December 2023
| in press
Journal Article
Control of mitochondrial dynamics by a fusogenic lipid
Abstract
Mitochondrial fusion enables cooperation between the mitochondrial population and is critical for mitochondrial function. Phosphatidic acid (PA) on the mitochondrial surface has a key role in mitochondrial fusion. A recent study by Su et al. shows that the nucleoside diphosphate (NDP) kinase NME3 recognizes PA and mediates its effects on mitochondrial dynamics.
Copyright and License
© 2023 Elsevier.
Acknowledgement
This work was supported by the NIH grant R35GM127147.
Conflict of Interest
The authors have no conflicts of interest to declare.
Additional details
- PMCID
- PMC10841390
- National Institutes of Health
- R35GM127147
- Caltech groups
- Division of Biology and Biological Engineering, Tianqiao and Chrissy Chen Institute for Neuroscience