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Published December 2023 | Version in press
Journal Article Metadata-only

Control of mitochondrial dynamics by a fusogenic lipid

Creators

  • 1. ROR icon California Institute of Technology

Abstract

Mitochondrial fusion enables cooperation between the mitochondrial population and is critical for mitochondrial function. Phosphatidic acid (PA) on the mitochondrial surface has a key role in mitochondrial fusion. A recent study by Su et al. shows that the nucleoside diphosphate (NDP) kinase NME3 recognizes PA and mediates its effects on mitochondrial dynamics.

Copyright and License

© 2023 Elsevier.

Acknowledgement

This work was supported by the NIH grant R35GM127147.

Conflict of Interest

The authors have no conflicts of interest to declare.

Additional details

Identifiers

PMCID
PMC10841390

Funding

National Institutes of Health
R35GM127147

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Caltech groups
Division of Biology and Biological Engineering (BBE), Tianqiao and Chrissy Chen Institute for Neuroscience