The commitment of the human cell atlas to humanity

Creators: Amit, Ido¹; Ardlie, Kristin²; Arzuaga, Fabiana³; Awandare, Gordon⁴; Bader, Gary⁵; Bernier, Alexander⁶; Carninci, Piero^{7, 8}; Donnelly, Stacey²; Eils, Roland⁹; Forrest, Alistair R. R.¹⁰; Greely, Henry T.¹¹; Guigo, Roderic¹²; Hacohen, Nir¹³; Haniffa, Muzlifah¹⁴; Kirby, Emily Sarah⁶; Knoppers, Bartha Maria⁶; Kriegstein, Arnold¹⁵; Lein, Ed S.¹⁶; Linnarsson, Sten¹⁷; Majumder, Partha P.^{18, 19}; Merad, Miriam²⁰; Meyer, Kerstin¹⁴; Mhlanga, Musa M.²¹; Nolan, Garry¹¹; Ntusi, Ntobeko A. B.^{22, 23}; Pe'er, Dana²⁴; Prabhakar, Shyam²⁵; Raven-Adams, Maili¹⁴; Regev, Aviv²⁶; Rozenblatt-Rosen, Orit²⁶; Saha, Senjuti²⁷; Saltzman, Andrea²; Shalek, Alex K.^{2, 28}; Shin, Jay W.²⁵; Stunnenberg, Henk²¹; Teichmann, Sarah A.¹⁴; Tickle, Timothy²; Villani, Alexandra-Chloe¹³; Wells, Christine²⁹; Wold, Barbara J.³⁰; Yang, Huanming³¹; Zhuang, Xiaowei³²

1. Weizmann Institute of Science
2. Broad Institute
3. Ministry of Science, Technology and Productive Innovation
4. University of Ghana
5. University of Toronto
6. McGill University
7. RIKEN Center for Integrative Medical Sciences
8. Human Technopole
9. BIH@Charité - Center for Digital Health, Berlin, Ethiopia
10. Harry Perkins Institute of Medical Research
11. Stanford University
12. Center for Genomic Regulation, Universitat Pompeu Fabra, Barcelona, Spain
13. Massachusetts General Hospital
14. Wellcome Sanger Institute
15. University of California, San Francisco
16. University of Washington
17. Karolinska Institutet Innovations (Sweden)
18. John C. Martin Centre for Liver Research & Innovation, Kolkata, India
19. Indian Statistical Institute
20. Icahn School of Medicine at Mount Sinai
21. Radboud Institute for Molecular Life Sciences
22. University of Cape Town
23. South African Medical Research Council
24. Memorial Sloan Kettering Cancer Center
25. Genome Institute of Singapore
26. Human Cell Atlas, South San Francisco, USA
27. Child Health Research Foundation
28. Massachusetts Institute of Technology
29. University of Melbourne
30. California Institute of Technology
31. BGI Group (China)
32. Harvard University

Abstract

The Human Cell Atlas (HCA) is a global partnership "to create comprehensive reference maps of all human cells—the fundamental units of life – as a basis for both understanding human health and diagnosing, monitoring, and treating disease." (https://www.humancellatlas.org/) The atlas shall characterize cells from diverse individuals across the globe to better understand human biology. HCA proactively considers the priorities of, and benefits accrued to, contributing communities. Here, we lay out principles and action items that have been adopted to affirm HCA's commitment to equity so that the atlas is beneficial to all of humanity.

Copyright and License

© 2024, The Author(s). This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.

Acknowledgement

An earlier version of this manuscript was archived on Open Science Forum; DOI 10.17605/OSF.IO/EZVC5; https://osf.io/sk697/. There is considerable overlap in the narratives of this manuscript with the archived version. We have not placed the overlapping text within quotes and have not referenced the archived version in this manuscript. We are grateful to Tracey Andrew, John Randell, Kristine Schwenck, Ellen Todres and Samantha Wynne, for help, suggestions and support. Figure 1 is licensed under Creative Commons CC BY-ND 4.0. This publication is part of the Human Cell Atlas: www.humancellatlas.org/publications/.

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