Computer programs for analysis of nucleic acid hybridization, thermal denaturation, and gel electrophoresis data

Abstract

Computer programs for the analysis of data from techniques frequently used in nucleic acids research are described. In addition to calculating non-linear least-squares solutions to equations describing these systems, the programs allow for data editing, normalization, plotting and storage, and are flexible and simple to use. Typical applications of the programs are described.

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Copyright © 1979 Oxford University Press. Received April 17, 1979. We thank T.D. Sargent, J.W. Posakony and R.B. Wallace for helpful discussion and critical review of this manuscript. This research was supported by U.S. Public Health Service Grants GM-13762 and GM-00086.

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