Welcome to the new version of CaltechAUTHORS. Login is currently restricted to library staff. If you notice any issues, please email coda@library.caltech.edu
Published July 1, 1961 | public
Journal Article Open

The effects of pressure on the buoyant behavior of deoxyribonucleic acid and tobacco mosaic virus in a density gradient at equilibrium in the ultracentrifuge


In the original analysis(1) of the behavior of macromolecules and viruses in a buoyant density gradient at equilibrium in the ultracentrifuge, all components were assumed to be incompressible. As a few hundred atmospheres are normally generated in the liquid, it is to be expected that previous results based on the assumption of incompressibility require re-examination.

Additional Information

© 1961 by the National Academy of Sciences. Communicated by Linus Pauling, May 29, 1961. This investigation was supported in part by Research Grant H-3394 from the National Institutes of Health, U.S. Public Health Service. [J.E.H. was a] Predoctoral Fellow of the National Science Foundation. [J.B.I. was a] U.S. Public Health Service Research Fellow of the Division of General Medical Sciences. Gates and Crellin Laboratories of Chemistry, Contribtion No. 2701.


Files (1.4 MB)
Name Size Download all
1.4 MB Preview Download

Additional details

August 21, 2023
October 16, 2023