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Published October 14, 1988 | public
Journal Article

DNA diagnostics--molecular techniques and automation


Molecular biology has revolutionized the understanding of many aspects of human disease. Ongoing developments in DNA diagnostics--the analysis of disease at the nucleic acid level--will soon provide automated, rapid, and inexpensive analyses for DNA or RNA sequences associated with genetic, malignant, and infectious diseases. DNA diagnostics will also facilitate the identification of disease-associated genes at birth, thus creating new opportunities for preventive medicine.

Additional Information

© 1988 American Association for the Advancement of Science. The authors gratefully acknowledge support from NSF to U.L., R.K., and L.H. and from NIH, the Muscular Dystrophy Foundation, and Howard Hughes Medical Institute to C.T.C. We thank N. Arnheim, W. Grody, C. Epstein, J. Korenberg, and M. Muldoon for useful advice. C. Hoog, T. Hunkapiller, W. Laug, D. Nickerson, and B. Popko offered helpful criticism on the manuscript.

Additional details

August 19, 2023
October 19, 2023