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Published February 1993 | public
Journal Article

Cell and molecular biology of neural crest cell lineage diversification


Neural crest cells are multipotent progenitor cells, but it is not understood how these cells generate their diverse differentiated progeny. This review considers the issues of whether neural crest cells self-renew, whether they generate partially committed intermediate progenitors, and how the local embryonic environment may act to control this diversification process. Novel molecular markers for neural crest cells are also discussed.

Additional Information

© 1993 Current Biology Ltd. I thank D Stemple, R Axel and S Fraser for helpful discussions, and P Patterson for making available a draft of his article on neural crest development for Current Opinion in Cell Biology.

Additional details

August 20, 2023
October 23, 2023