Patches with Links: A Unified System for Processing Faces in the Macaque Temporal Lobe
Abstract
The brain processes objects through a series of regions along the ventral visual pathway, but the circuitry subserving the analysis of specific complex forms remains unknown. One complex form category, faces, selectively activates six patches of cortex in the macaque ventral pathway. To identify the connectivity of these face patches, we used electrical microstimulation combined with simultaneous functional magnetic resonance imaging. Stimulation of each of four targeted face patches produced strong activation, specifically within a subset of the other face patches. Stimulation outside the face patches produced an activation pattern that spared the face patches. These results suggest that the face patches form a strongly and specifically interconnected hierarchical network.
Additional Information
© 2008 American Association for the Advancement of Science. Received 6 March 2008; accepted 7 May 2008. We are grateful to the late David Freeman and to M. Livingstone, who programmed and designed the visual stimulus presentation software RF3; to N. Schweers, K. Thoss, and R. Hakizimana for technical support; to S. Everling for advice on microstimulation; to M. Livingstone and K. S. Saleem for comments on the manuscript; and to Guerbet for providing Sinerem. This work was supported by a Sofia Kovalevskaya Award from the Alexander von Humboldt Foundation; by the German Science Foundation (DFG FR1437/3-1); and by the German Ministry of Science (grant no. 01GO0506, Bremen Center for Advanced Imaging).Attached Files
Accepted Version - Moeller2008_Science.pdf
Supplemental Material - Moeller.SOM.pdf
Files
| Name | Size | Download all |
|---|---|---|
|
md5:e9f1bec1b8d97d06d77e66f3ea39e3ab
|
7.5 MB | Preview Download |
|
md5:5226121fcf9bc3b438275d3d54b1cae9
|
23.4 MB | Preview Download |
Additional details
- Eprint ID
- 100895
- DOI
- 10.1126/science.1157436
- Resolver ID
- CaltechAUTHORS:20200124-095901977
- Alexander von Humboldt Foundation
- Deutsche Forschungsgemeinschaft (DFG)
- FR1437/3-1
- Bundesministerium für Bildung und Forschung (BMBF)
- 01GO0506
- Created
-
2020-01-24Created from EPrint's datestamp field
- Updated
-
2021-05-03Created from EPrint's last_modified field