Welcome to the new version of CaltechAUTHORS. Login is currently restricted to library staff. If you notice any issues, please email coda@library.caltech.edu
Published April 2015 | public
Book Section - Chapter

Measurement of viscosity of unadulterated human whole blood using a capillary pressure-driven viscometer


This paper presents the experimental work on the measurement of unadulterated human whole blood viscosity using a capillary-based microfluidic viscometer. The viscosity was measured by monitoring the time-varying length and mean advancing velocity of the blood column inside the viscometer. A high-aspect-ratio microfluidic channel is preferred for the device geometrical configuration. Theoretical modeling and numerical algorithms were applied to obtain the blood viscosity over a wide range of shear rates. Power law and Carreau-Yasuda models were used to model the non-Newtonian behavior of the human whole blood. The proposed approach is uniquely applicable for small sample volume (<2µL), and short measurement time (<2 min). A wide range of shear rates (varying from of 71.4s^(−1) to 5492.1s^(−1)) is produced in a single test.

Additional Information

© 2015 IEEE. The authors gratefully acknowledge the help from all the members of the Caltech Micromachining Lab and the UCLA Cardiovascular Engineering Research Laboratory.

Additional details

August 22, 2023
October 23, 2023