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Published April 2004 | Published
Book Section - Chapter Open

High-resolution functional photoacoustic tomography


All-optical imaging has high contrast but poor spatial resolution beyond the ballistic and quasiballistic regimes. All-ultrasonic imaging has high spatial resolution but poor contrast for early stage tumors. Photoacoustic tomography combines the high optical contrast and the high ultrasonic resolution. Our work in this emerging area of research will be summarized in this invited talk. In this technology, a diffraction-based inverse-source problem is solved in the image reconstruction, for which our group developed the rigorous reconstruction theory. We developed a prototype and accomplished noninvasive transdermal and transcranial functional imaging of small-animal brains in vivo.

Additional Information

© 2004 IEEE. This project was sponsored in part by the U.S. Army Medical Research and Materiel Command Grant No. DAMD17-00-1-0455 the National Institutes of Health Grants No. R01 EB000712 and No. R01 NS46214, and Texas Higher Education Coordinating Board Grant No. ARP 000512-0063-2001.

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