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Published October 1973 | public
Journal Article

Redistribution of histones during unfolding of chromosomal DNA


Just in the course of unfolding of chromosomal deoxyribonucleoproteins performed in the absence of magnesium ions all DNA-bound histones may be redistributed. This type of redistribution is completely blocked in already 'unfolded' DNP preparations. If the unfolding-induced histone redistribution is allowed it leads to a significant decrease of the average length of free DNA segments in the unfolded, histone F1-depleted DNP. The implications of these data on the mode of DNA packing in chromatin are discussed.

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© 1973 Springer. Received 07 August 1973.

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October 23, 2023