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Published March 11, 2015 | Published
Book Section - Chapter Open

Photoacoustic microscopy of complex regional pain syndrome type I (CRPS-1) after stellate ganglion blocks in vivo


We used photoacoustic microscopy (PAM) to assist diagnoses and monitor the progress and treatment outcome of complex regional pain syndrome type 1 (CRPS-1). Blood vasculature and oxygen saturation (sO_2) were imaged by PAM in eight adult patients with CRPS-1. Patients' hands and cuticles were imaged both before and after stellate ganglion block (SGB) for comparison. For all patients, both the vascular structure and sO_2 could be assessed by PAM. In addition, more vessels and stronger signals were observed after SGB.

Additional Information

© 2015 Society of Photo-Optical Instrumentation Engineers. The authors would like to thank Prof. James Ballard for manuscript editing. This work was sponsored in part by National Institutes of Health grants DP1 EB016986 (NIH Director's Pioneer Award), R01 CA186567 (NIH Director's Transformative Research Award), and R01 CA159959. Maslov, Konstantin: Microphotoacoustics, Inc., which, however, did not support this work; Wang, Lihong: Microphotoacoustics, Inc. and Endra, Inc., which, however, did not support this work.

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