Published July 23, 2014 | Version Accepted Version + Supplemental Material
Journal Article Open

Fully Loaded Micromotors for Combinatorial Delivery and Autonomous Release of Cargoes

Abstract

Integrating functional self-propelled Zinc micromotors are created by coup­ling electrodeposition with hard dual-templating synthesis. The micromotors concurrently possess four robust functions including a remarkably high loading capacity, combinatorial delivery of cargoes, autonomous release of encapsulated payloads, and self-destruction. This concept could be expanded to simultaneous encapsulation of various payloads for different functionalities such as therapy, diagnostics, and imaging.

Additional Information

© 2014 Wiley. Received: November 25, 2013. Published online: April 6, 2014. This project received support from the Defense Threat Reduction Agency-Joint Science and Technology Office for Chemical and Biological Defense (Grant no. HDTRA1–13–1–0002). L. Z. acknowledges the funding support from the National Institute of Diabetes and Digestive and Kidney Diseases of the National Institutes of Health under Award Number R01DK095168. H. K. acknowledges the China Scholarship Council (CSC) for the financial support. W. G. is a HHMI International Student Research fellow. S. S. and H. K. contributed equally to this work.

Attached Files

Accepted Version - nihms588726.pdf

Supplemental Material - smll201303646-sup-0001-S1.pdf

Supplemental Material - smll201303646-sup-0002-S2.mov

Supplemental Material - smll201303646-sup-0003-S3.mov

Supplemental Material - smll201303646-sup-0004-S4.mov

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Additional details

Identifiers

PMCID
PMC4107182
Eprint ID
84468
Resolver ID
CaltechAUTHORS:20180123-083721087

Funding

Defense Threat Reduction Agency (DTRA)
HDTRA1–13–1–0002
NIH
R01DK095168
China Scholarship Council
Howard Hughes Medical Institute (HHMI)

Dates

Created
2018-02-01
Created from EPrint's datestamp field
Updated
2021-11-15
Created from EPrint's last_modified field